S. C. Bodine

This study shows testosterone is not essential for maintaining muscle mass in adult male mice but is crucial for young mice's muscle growth.

This study shows that knocking down UBR5 leads to skeletal muscle atrophy by disrupting anabolic signaling pathways.

This study identifies Fbxl22 and its splice variant as E3 ubiquitin ligases involved in neurogenic muscle atrophy, showing their role in muscle atrophy and potential therapeutic relevance.

This paper identifies UBR5 as a novel E3 ubiquitin ligase inversely regulated to MuRF1/MAFbx, epigenetically modulated during skeletal muscle recovery from atrophy and hypertrophy, and genetically associated with muscle fiber size and strength traits.