Author

S. Case

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. L. Gorman· 1 shared A. P. Bracken· 1 shared B. Stojkovic· 1 shared C. Drews· 1 shared C. Frezza· 1 shared D. G. Ryan· 1 shared E. C. Lavelle· 1 shared E. Lagan· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

A. L. Gorman

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2 papers

Recent·Most cited

Macrophage Innate Training Induced by IL-4 and IL-13 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses

M. L. Lundahl, M. Mitermite, D. G. Ryan, S. Case, N. C. Williams, M. Yang, R. I. Lynch, E. Lagan, F. M. Lebre, A. L. Gorman, B. Stojkovic, A. P. Bracken, C. Frezza, F. J. Sheedy, E. M. Scanlan, , E. C. Lavelle

This study shows that IL-4 and IL-13 activation of macrophages induces protective innate memory against mycobacterial infection through enhanced OXPHOS-driven pro-inflammatory responses.

bioRxiv · Oct 12, 2021Immunology

E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/β-catenin pathway through E6AP-dependent degradation of NHERF1

C. Drews, S. Case, S. Vande Pol

This paper identifies NHERF1 as a conserved target of degradation by both high- and low-risk HPV E6 proteins and animal papillomavirus E6 proteins, leading to activation of the Wnt/β-catenin pathway.

bioRxiv · Jan 11, 2019Microbiology