ImmunologybioRxiv
Macrophage Innate Training Induced by IL-4 and IL-13 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses
M. L. Lundahl, M. Mitermite, D. G. Ryan…·E. C. Lavelle
This study shows that IL-4 and IL-13 activation of macrophages induces protective innate memory against mycobacterial infection through enhanced OXPHOS-driven pro-inflammatory responses.