Author

E. Lagan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. P. Bracken· 2 shared A. Doherty· 1 shared A. J. Silva· 1 shared A. L. Gorman· 1 shared A. Vanderlinden Dibekeme· 1 shared B. Chen· 1 shared B. Stojkovic· 1 shared C. Frezza· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

A. P. Bracken

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Author profile →

2 papers

Recent·Most cited

Specific cPRC1 complexes are co-opted to mediate oncogenic gene repression in diffuse midline glioma

D. Gannon, E. Lagan, A. J. Silva, P. Bibawi, A. Doherty, D. Nimmo, R. McCole, C. Monger, G. Genesi, A. Vanderlinden Dibekeme, J. Innes, L. Yang, B. Chen, G. van Mierlo, P. W. Jansen, , G. Brien

The paper identifies specific cPRC1 complexes, CBX4/PCGF4, that mediate oncogenic gene repression in DMG cells downstream of H3K27M mutation.

bioRxiv · Dec 2, 2023Cancer Biology

Macrophage Innate Training Induced by IL-4 and IL-13 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses

M. L. Lundahl, M. Mitermite, D. G. Ryan, S. Case, N. C. Williams, M. Yang, R. I. Lynch, E. Lagan, F. M. Lebre, A. L. Gorman, B. Stojkovic, A. P. Bracken, C. Frezza, F. J. Sheedy, E. M. Scanlan, , E. C. Lavelle

This study shows that IL-4 and IL-13 activation of macrophages induces protective innate memory against mycobacterial infection through enhanced OXPHOS-driven pro-inflammatory responses.

bioRxiv · Oct 12, 2021Immunology