Author

S. Cha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. A. Tzika· 2 shared A. Chakraborty· 2 shared L. Rahme· 2 shared A. Bandyopadhaya· 1 shared A. Dimitriou· 1 shared C. M. de Crescenzo· 1 shared D.-C. Woo· 1 shared F. Kovacic· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. A. Tzika

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Skeletal Muscle Mitochondrial Dysfunction Mediated by Pseudomonas aeruginosa Quorum Sensing Transcription Factor MvfR: Reversing Effects with Anti-MvfR and Mitochondrial-Targeted Compounds

L. Rahme, S. Aggarwal, V. K. Singh, A. Chakraborty, S. Cha, A. Dimitriou, C. M. de Crescenzo, O. Izikson, L. Yu, R. Plebani, A. A. Tzika

This study investigates how Pseudomonas aeruginosa's MvfR quorum sensing transcription factor disrupts mitochondrial function in skeletal muscle and shows that inhibiting MvfR or using mitochondrial-targeted compounds can reverse these effects.

bioRxiv · May 3, 2024 · PreprintMicrobiology

The Bacterial Quorum-Sensing Signal 2-Aminoacetophenone Rewires Immune Cell Bioenergetics through the PGC-1α/ERRα Axis to Mediate Tolerance to Infection

A. Chakraborty, A. Bandyopadhaya, V. Singh, F. Kovacic, S. Cha, W. Oldham, A. A. Tzika, L. Rahme

This study shows that the bacterial QS signal 2-AA modulates immune cell bioenergetics via the PGC-1α/ERRα axis, promoting immune tolerance and pathogen persistence.

bioRxiv · Feb 26, 2024Immunology

Impact of Cervical Lymphatic Obstruction on Brain Pathophysiology in Cervical Lymphedema Animal Models

H. Cheon, D.-C. Woo, S. Cha, Y. J. Chae, I. Maeng, S. J. Oh, J. Y. Jeon

This study shows that cervical lymphatic obstruction in rats leads to brain swelling, increased cerebrospinal fluid, and tissue water content, resembling hydrocephalus and cerebral edema.

bioRxiv · Feb 21, 2024 · PreprintPhysiology

Cost implications of a nationwide survey of schistosomiasis and other intestinal helminthiases in Sudan

M. S. Elhag, Y. Jin, M. A. Amin, H. A. H. A. Ismail, S.-T. Hong, H. Jang, Y.-A. Doh, S. Cha

This study reports the financial and economic costs of a nationwide schistosomiasis and intestinal helminthiases survey in Sudan, identifying personnel and transportation as key cost drivers.

bioRxiv · Dec 4, 2019Microbiology