Two ligand-binding sites on SARS-CoV-2 non-structural protein 1 revealed by fragment-based x-ray screening
S. Ma, S. Damfo, J. Lou, N. Pinotsis, M. W. Bowler, S. Haider, F. G. Kozielski
This study identifies two ligand-binding sites on SARS-CoV-2 nsp1 using X-ray crystallography and fragment-based screening, offering a foundation for inhibitor development.
bioRxiv · Jun 12, 2022Biochemistry