MicrobiologybioRxiv
ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model
K. Vandyck, R. Abdelnabi, K. Gupta…·J. Neyts
This study evaluates ALG-097111, a selective SARS-CoV-2 3CLpro inhibitor, showing potent in vitro activity and significant in vivo antiviral effects in Syrian hamsters.
DOI 10.1016/j.bbrc.2021.03.096