Author

S. Dowson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

C. Gourley· 2 shared I. A. McNeish· 2 shared A. Clamp· 1 shared A. Ewing· 1 shared A. Hanif· 1 shared A. Hoyle· 1 shared A. M. Piskorz· 1 shared A. Matakidou· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

C. Gourley

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2 papers

Recent·Most cited

Structural variants at the BRCA1/2 loci are a common source of homologous repair deficiency in high grade serous ovarian carcinoma

A. Ewing, A. Meynert, M. Churchman, G. R. Grimes, R. L. Hollis, C. S. Herrington, T. Rye, C. Bartos, I. Croy, M. Ferguson, M. Lennie, T. McGoldrick, N. McPhail, N. Siddiqui, S. Dowson, , C. A. Semple

This study identifies large structural variants as a significant source of homologous repair deficiency in high-grade serous ovarian carcinoma, beyond known SNVs and indels at BRCA1/2.

bioRxiv · May 11, 2020Cancer Biology

Copy-number signatures and mutational processes in ovarian carcinoma

G. Macintyre, T. Goranova, D. De Silva, D. Ennis, A. M. Piskorz, M. Eldridge, D. Sie, L.-A. Lewsley, A. Hanif, C. Wilson, S. Dowson, R. M. Glasspool, M. Lockley, E. Brockbank, A. Montes, , J. D. Brenton

This study identifies copy-number signatures in ovarian cancer and links them to mutational processes, showing that most cases involve multiple processes, suggesting therapeutic challenges.

bioRxiv · Sep 4, 2017Cancer Biology