Pharmacology & ToxicologybioRxiv
A repurposed drug screen identifies compounds that inhibit the binding of the COVID-19 spike protein to ACE2
K. B. Tsegay, C. M. Adeyemi, E. P. Gniffke…·S. E. P. Smith
The paper screens 2701 approved drugs to find those inhibiting SARS-CoV-2 spike protein binding to ACE2, identifying 56 compounds with >90% inhibition and modeling their docking.
DOI 10.3389/fphar.2021.685308