Author

S. E. Sevdalis

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Biophysics· 1

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Approach:experimental assay· 1

Frequent Co-Authors

A. des Georges· 1 shared A. X. Spittel· 1 shared D. J. Weber· 1 shared D. L. Abeyawardhane· 1 shared E. Pozharski· 1 shared I. F. Nawaz· 1 shared K. A. Adipietro· 1 shared K. M. Varney· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiophysics

A. des Georges

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 18, 2023

Membrane binding and pore formation is Ca2+-dependent for the Clostridioides difficile binary toxin

D. L. Abeyawardhane, S. E. Sevdalis, K. A. Adipietro…·D. J. Weber

This study shows that Ca2+ dissociation from CDTb's RBD1 triggers pore formation in endosomal membranes, differing from other binary toxins that rely on pH changes.

DOI 10.1101/2023.08.18.553786

experimental assay

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