Author

S. Emond

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

F. Hollfelder· 3 shared A. Buchanan· 1 shared B. Heames· 1 shared B. Popovic· 1 shared D. Cannon· 1 shared D. G. Rees· 1 shared E. Kay· 1 shared J. Andrews· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiochemistry

F. Hollfelder

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Author profile →

3 papers

Recent·Most cited

Versatile Product Detection via Coupled Assays for Ultra-high-throughput Screening of Carbohydrate-Active-Enzymes in Microfluidic Droplets

S. Ladeveze, P. Zurek, T. Kaminski, S. Emond, F. Hollfelder

This paper develops microfluidic droplet assays to enable ultra-high-throughput screening of carbohydrate-active enzymes by detecting unlabelled carbohydrate products through optical signals.

bioRxiv · Mar 29, 2023 · PreprintBiochemistry

In vitro Evolution of Antibody Affinity via Insertional Mutagenesis Scanning of an Entire Antibody Variable Region

K. Skamaki, S. Emond, M. Chodorge, J. Andrews, D. G. Rees, D. Cannon, B. Popovic, A. Buchanan, R. Minter, F. Hollfelder

This paper demonstrates that insertional mutagenesis can enhance antibody affinity, achieving a 256-fold improvement in an anti-IL-13 antibody through InDel mutagenesis combined with point mutations.

bioRxiv · Apr 26, 2020Biochemistry

Access to unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis

S. Emond, M. Petek, E. Kay, B. Heames, S. Devenish, N. Tokuriki, F. Hollfelder

This study introduces TRIAD, a transposon mutagenesis method to generate InDels for directed enzyme evolution, showing distinct functional outcomes compared to point mutagenesis.

bioRxiv · Oct 10, 2019Biochemistry