Author

S. Devenish

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

C. M. Dobson· 2 shared A. S. Morgunov· 1 shared B. Heames· 1 shared C. K. Xu· 1 shared E. Kay· 1 shared E. Sileikis· 1 shared F. Hollfelder· 1 shared F. Qian· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

C. M. Dobson

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Author profile →

4 papers

Recent·Most cited

Machine learning aided top-down protein identification on a microfluidic platform

Y. Zhang, M. Wright, K. L. Saar, P. Challa, A. S. Morgunov, Q. A. E. Peter, S. Devenish, C. M. Dobson, T. P. J. Knowles

This paper demonstrates a microfluidic platform that generates multidimensional protein fingerprints, enabling high-accuracy classification using machine learning, even when single-dimensional classification fails.

bioRxiv · Nov 14, 2020 · PreprintBiophysics

Kinetic fingerprints differentiate anti-Aβ therapies

S. Linse, T. Scheidt, K. Bernfur, M. Vendruscolo, C. M. Dobson, S. I. Cohen, E. Sileikis, M. Lundquist, F. Qian, T. O'Malley, T. Bussiere, P. H. Weinreb, C. K. Xu, G. Meisl, S. Devenish, , O. Hansson

This study uses kinetic analysis and binding measurements to compare four anti-Aβ antibodies, showing aducanumab uniquely reduces Aβ oligomer flux.

bioRxiv · Feb 27, 2020 · PreprintBiophysics

Access to unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis

S. Emond, M. Petek, E. Kay, B. Heames, S. Devenish, N. Tokuriki, F. Hollfelder

This study introduces TRIAD, a transposon mutagenesis method to generate InDels for directed enzyme evolution, showing distinct functional outcomes compared to point mutagenesis.

bioRxiv · Oct 10, 2019Biochemistry

Cannabichromene is a cannabinoid CB2 receptor agonist

M. P. Udoh, M. J. Santiago, S. Devenish, I. S. McGregor, M. Connor

This study identifies cannabichromene (CBC) as a selective CB2 receptor agonist with higher efficacy than THC in hyperpolarizing AtT20 cells.

bioRxiv · Nov 27, 2018Pharmacology & Toxicology