Cell BiologybioRxiv
Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins
K. Ehring, S. F. Ehlers, J. Froese…·K. Grobe
This study shows that Dispatched (Disp) mediates the shedding and transfer of cholesterol-modified Sonic hedgehog (Shh) to high-density lipoproteins (HDL), with HDL-associated Shh being highly bioactive.
DOI 10.7554/elife.86920.4