Author

S. F. Flanigan

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Biochemistry· 1

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

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B. M. Owen· 1 shared C. Davidovich· 1 shared Q. Zhang· 1 shared S. C. Agius· 1 shared V. Levina· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperBiochemistry

B. M. Owen

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1 paper

Recent·Most cited

BiochemistrybioRxivMay 28, 2020

Convergent evolution between PALI1 and JARID2 for the allosteric activation of PRC2

Q. Zhang, S. C. Agius, S. F. Flanigan…·C. Davidovich

This study shows that PALI1, a vertebrate-specific PRC2 accessory subunit, convergently evolved to function like JARID2 by allosterically activating PRC2 through methylation and DNA binding.

DOI 10.1038/s41467-021-24866-3

humanmouse

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