Author

S. Fromm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Bendes· 1 shared A. Elofsson· 1 shared A. Martinez-Sanchez· 1 shared A. Mayer· 1 shared C. Sachse· 1 shared D. Mann· 1 shared I. Kotliar· 1 shared J. H. Hurley· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Bendes

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multiplexed selectivity screening of anti-GPCR antibodies

L. Dahl, I. Kotliar, A. Bendes, T. Dodig-Crnkovic, S. Fromm, A. Elofsson, M. Uhlen, T. P. Sakmar, J. Schwenk

The paper screens 400 anti-GPCR antibodies for selectivity using a multiplexed immunoassay against 215 solubilized GPCRs, finding 61% are selective, 11% bind off-target, and 28% bind none.

bioRxiv · Nov 24, 2022Biochemistry

Structural plasticity of Atg18 oligomers: organization of assembled tubes and scaffolds at the isolation membrane

D. Mann, S. Fromm, A. Martinez-Sanchez, N. Gopaldass, A. Mayer, C. Sachse

This study determines the cryo-EM structures of Atg18 oligomers and their interactions with lipid membranes, revealing their role in coordinating autophagy machinery components.

bioRxiv · Jul 26, 2022 · PreprintBiophysics

Structural mechanism for amino acid-dependent Rag GTPase switching by SLC38A9

S. Fromm, R. E. Lawrence, J. H. Hurley

This paper reveals how SLC38A9 destabilizes the lysosomal FLC complex to promote Rag dimer activation by disrupting the GAP activity toward RagC.

bioRxiv · Jul 28, 2020Biochemistry