Author

S. G. Murphy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

F. Cava· 2 shared J.-H. Shin· 2 shared L. Alvarez· 2 shared T. Doerr· 2 shared T. Dörr· 2 shared A. I. Weaver· 1 shared A. N. Murtha· 1 shared B. A. Johnson· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

F. Cava

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Class A Penicillin-Binding Protein-mediated cell wall synthesis promotes structural integrity during peptidoglycan endopeptidase insufficiency

S. G. Murphy, A. N. Murtha, Z. Zhao, L. Alvarez, P. Diebold, J.-H. Shin, M. S. VanNieuwenhze, F. Cava, T. Doerr

This study investigates the role of endopeptidases and class A PBPs in PG synthesis and structural integrity in V. cholerae, showing that aPBPs can compensate for EP insufficiency.

mBio · Apr 27, 2021Peer-reviewedMicrobiology

Vibrio cholerae's mysterious Seventh Pandemic island (VSP-II) encodes novel Zur-regulated zinc starvation genes involved in chemotaxis and autoaggregation

S. G. Murphy, B. A. Johnson, C. M. Ledoux, T. Doerr

This study identifies zinc starvation as an inducer of VSP-II gene expression in V. cholerae, revealing a transcriptional network involving VerA and AerB that drives autoaggregation and aerotaxis.

bioRxiv · Mar 9, 2021Microbiology

Endopeptidase regulation as a novel function of the Zur-dependent zinc starvation response

S. G. Murphy, L. Alvarez, M. C. Adams, S. Liu, J. S. Chappie, F. Cava, T. Dörr

This paper identifies ShyB, a zinc-dependent endopeptidase in Vibrio cholerae, as a novel component of the Zur-mediated zinc starvation response that sustains cell growth under low-zinc conditions.

bioRxiv · Sep 3, 2018Microbiology

Genetic determinants of penicillin tolerance in Vibrio cholerae

A. I. Weaver, S. G. Murphy, B. Umans, S. Tallavajhala, I. Onyekwere, S. Wittels, J.-H. Shin, M. VanNieuwenhze, M. K. Waldor, T. Dörr

This study identifies genetic factors in Vibrio cholerae that contribute to penicillin tolerance and post-antibiotic recovery.

bioRxiv · Jun 4, 2018Microbiology