MicrobiologybioRxiv
High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications.
A. N. Murtha, M. I. Kazi, R. D. Schargel…·T. Dörr
This paper identifies PhoPQ-mediated LPS modifications as a mechanism for carbapenem tolerance in Enterobacterales, showing that antibiotic-induced outer membrane changes enhance survival.
DOI 10.1371/journal.ppat.1010307