Structure of human ferroportin bound to hepcidin reveals mechanisms of iron homeostasis
C. Billesboelle, C. Azumaya, R. C. Kretsch, A. S. Powers, S. Gonen, S. Schneider, T. Arvedson, R. Dror, Y. Cheng, A. Manglik
This study determines the cryo-EM structures of human ferroportin bound to hepcidin and identifies mechanisms of iron homeostasis regulation.
bioRxiv · Mar 16, 2020 · PreprintBiochemistry