S. Schneider

Assessing Lanthanide-Dependent Methanol Dehydrogenase Activity: The Assay Matters

The paper compares two assays for measuring Ln-dependent MDH activity, showing different trends in enzyme activity based on the assay used.

Single Nucleus Sequencing of Human Colon Visceral Smooth Muscle Cells, PDGFRα Cells, and Interstitial Cells of Cajal

The paper performs single-nucleus RNA sequencing on human colon SIP syncytium cells to identify novel features and gene expression differences across cell types and bowel regions.

Structure and mechanism of the RNA dependent RNase Cas13a from Rhodobacter capsulatus

This study characterizes the structure and mechanism of RcCas13a, an RNA-dependent RNA endonuclease from Rhodobacter capsulatus, revealing its crRNA recognition, activation conformation, and cleavage mechanism.

Percolation of Microparticle Matrix Promotes Cell Migration and Integration while Supporting Native Tissue Architecture

This study develops a composite biomaterial called tissue clay that supports cell migration and tissue integration while mimicking native architecture.

Structure of human ferroportin bound to hepcidin reveals mechanisms of iron homeostasis

This study determines the cryo-EM structures of human ferroportin bound to hepcidin and identifies mechanisms of iron homeostasis regulation.

WAT’s up!? – Organ-on-a-chip integrating human mature white adipose tissues for mechanistic research and pharmaceutical applications

The paper develops a WAT-on-a-chip system to study human white adipose tissue function and drug responses in obesity and diabetes.

GORAB, a Golgi protein required for centriole structure and duplication

The paper identifies Gorab as a Golgi protein essential for centriole structure and duplication, showing it has distinct roles in centriole and Golgi functions in Drosophila.