BiophysicsbioRxiv
Mechanism of transcription modulation by the transcription-repair coupling factor
B. P. Paudel, Z.-Q. Xu, S. Jergic…·H. Ghodke
This study investigates how the bacterial TRCF Mfd modulates transcription by converting elongation complexes into catalytically poised states and then irreversibly terminating transcription through ATP hydrolysis.