Author

S. Hiller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:structural biology· 3 Organism:bacteria (other)· 2 Approach:biophysical modeling· 2 Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2

Frequent Co-Authors

B. N. Dubey· 3 shared R. Boehm· 3 shared T. Schirmer· 3 shared U. Jenal· 3 shared A. Kaczmarczyk· 2 shared C. von Arx· 2 shared A. Basle· 1 shared A. Cartmell· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

B. N. Dubey

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Toxin-mediated depletion of nicotinamide dinucleotides drives persister formation in a human pathogen

I. Santi, R. Dias Teixeira, P. Manfredi, D. Spiess, G. Mas, A. Klotz, N. Zamboni, S. Hiller, U. Jenal

This study shows that the RES domain TA system in P. aeruginosa promotes persister formation by depleting NAD and NADP under nutrient stress, enhancing bacterial survival during antibiotic treatment.

bioRxiv · Sep 28, 2023 · PreprintMicrobiology

Intermediaries in phosphotransfer: structural features discriminating hybrid histidine kinase Rec domains from response regulator homologs

M. Bruederlin, R. Boehm, F. Fadel, S. Hiller, T. Schirmer, B. N. Dubey

The paper structures and analyzes the CckARec domain from C. crescentus to distinguish it from RR Rec domains, highlighting structural differences in phosphoryl-binding and absence of allosteric changes.

bioRxiv · Jun 3, 2022Biochemistry

Insights into glycan import by a prominent gut symbiont

D. Gray, J. White, A. Oluwole, P. Rath, A. Glenwright, A. Mazur, M. Zahn, A. Basle, C. Morland, S. Evans, A. Cartmell, C. V. Robinson, S. Hiller, N. Ranson, D. Bolam, B. van den Berg

This study characterizes the SusCD protein complex in Bacteroides thetaiotaomicron to elucidate its role in glycan uptake, revealing structural and functional insights into ligand binding and transport dynamics.

Nature Communications · Jan 4, 2021Peer-reviewedMicrobiology

Hybrid histidine kinase activation by cyclic di-GMP- mediated domain liberation

B. N. Dubey, E. Agustoni, R. Boehm, A. Kaczmarczyk, F. Mangia, C. von Arx, U. Jenal, S. Hiller, I. Plaza-Menacho, T. Schirmer

This study reveals how c-di-GMP regulates ShkA, a hybrid histidine kinase in Caulobacter crescentus, by inducing domain dissociation and allosteric activation.

bioRxiv · Jun 22, 2019Biochemistry

Precise transcription timing by a second-messenger drives a bacterial G1/S cell cycle transition

A. Kaczmarczyk, A. M. Hempel, C. von Arx, R. Boehm, B. N. Dubey, J. Nesper, T. Schirmer, S. Hiller, U. Jenal

This study identifies c-di-GMP as a second messenger that regulates the G1/S transition in Caulobacter crescentus by modulating ShkA and TacA activity.

bioRxiv · Jun 20, 2019Microbiology