TRAF2, an innate immune sensor, reciprocally regulates mitophagy and inflammation to maintain cardiac myocyte homeostasis.
X. Ma, D. R. Rawnsley, A. Kovacs, M. Islam, J. T. Murphy, C. Zhao, M. Kumari, L. M. Foroughi, H. Liu, K. Hyrc, S. Evans, B. A. French, K. B. Margulies, A. Javaheri, B. Razani, , A. Diwan
This study shows TRAF2 regulates mitophagy and inflammation in cardiac myocytes to prevent cell death and maintain homeostasis.
bioRxiv · Jun 12, 2021Cell Biology