Author

S. Izraeli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. Muschen· 2 shared A. Borkhard· 1 shared A. M. Savino· 1 shared A. Nagler· 1 shared A. P. Wiita· 1 shared A. Rein Gil· 1 shared A. Vogt· 1 shared C. Hong· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

M. Muschen

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2 papers

Recent·Most cited

Cancer BiologybioRxivMar 12, 2020

Signaling input from divergent pathways subverts malignant B-cell transformation

L. N. Chan, M. A. Murakami, M. E. Robinson…·M. Muschen

This study shows that malignant B-cell transformation requires convergence on a single oncogenic pathway, while divergent pathways can subvert transformation and are targets for new therapeutic strategies.

DOI 10.1182/blood-2019-130774

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 27, 2020

An instructive role for IL7RA in the development of human B-cell precursor leukemia.

I. Geron, A. M. Savino, N. Tal…·S. Izraeli

This study shows that aberrant IL7RA signaling in human hematopoietic progenitors leads to B-cell differentiation arrest and Ph-like BCP-ALL development in mice.

DOI 10.1101/2020.01.27.919951

humanbulk RNA-seq

𝕏 PostBluesky