S. J. Cleary

This study shows that IgG hexamerization is critical for triggering acute lung injury and suggests therapeutic strategies targeting hexamer formation.

This study compares pulmonary dosing efficiency in mice under different anesthetic and delivery methods, finding that ketamine/xylazine anesthesia and oropharyngeal aspiration improve lung delivery compared to isoflurane and intranasal dosing.

This study identifies CD98 as critical for inflammatory responses to injury stimuli in IPF exacerbations and COVID pneumonitis, showing its role in IL-6 and IL-8 responses and fibrosis progression.