C. Harris

Engineered Immunogens to Elicit Antibodies Against Conserved Coronavirus Epitopes

This study designs engineered immunogens targeting conserved coronavirus epitopes to elicit broad-spectrum antibodies, showing protection in mice against live virus challenge.

The Development and Validation of a Portable, Benchtop, Hydrostatic Model to Acquire and Analyze Quantitative Data on Unused and Failed Hydrocephalus Catheters

The paper develops and validates a hydrostatic model to measure flow resistance in hydrocephalus catheters, showing significant differences in resistance among catheter models and explanted catheters.

Audiovisual cues must be predictable and win-paired to drive risky choice

This study shows that audiovisual cues paired with wins increase risky choice in rats, but cues alone or with losses do not, suggesting reliable win-paired associations drive this behavior.

CD98 is critical for a conserved inflammatory response to diverse injury stimuli relevant to IPF exacerbations and COVID pneumonitis

This study identifies CD98 as critical for inflammatory responses to injury stimuli in IPF exacerbations and COVID pneumonitis, showing its role in IL-6 and IL-8 responses and fibrosis progression.

Applications of a Novel Reciprocating Positive Displacement Pump in the Simulation of Pulsatile Arterial Blood Flow

This paper verifies a novel reciprocating positive displacement pump for simulating pulsatile arterial blood flow in various organ systems with high accuracy.

Testing and Validation of Reciprocating Positive Displacement Pump for Benchtop Pulsating Flow Model of Cerebrospinal Fluid Production and Other Physiologic Systems

This paper validates a reciprocating positive displacement pump for simulating pulsatile cerebrospinal fluid flow in vitro, showing accurate volume output and control over pulsation rate and amplitude.

Validation of a small molecule inhibitor of PDE6D-RAS interaction with potent anti-leukemic effects

The paper identifies a small molecule inhibitor of PDE6D-RAS interaction that shows anti-leukemic effects by blocking RAC activation in RAS-mutated cells.

The Effect of A1/A2 Reactive Astrocyte Expression on Hydrocephalus Shunt Failure

This study examines the gene expression profiles of reactive astrocytes on hydrocephalus shunt surfaces at failure, finding a higher prevalence of A2 reactive astrocytes associated with obstruction.

Efficient, selectable marker free gene targeting in soybean using novel Ochrobactrum haywardense-mediated delivery

This paper develops a selectable marker-free gene targeting system in soybean using Ochrobactrum haywardense-mediated delivery, achieving 3.4% targeted insertion and 90% mutation rate in T0 plants.

Intrapopulation adaptive variance supports selective breeding in a reef-building coral

This study identifies genomic signatures of thermal tolerance in corals and shows that intrapopulation variance supports adaptive breeding under climate change.

Unique features of stimulus-based probabilistic reversal learning

This study compares discrimination and reversal learning in rats, finding distinct behavioral patterns and differences in reward sensitivity and learning rates between the two tasks.

Cadmium exposure inhibits branching morphogenesis and causes alterations consistent with HIF-1α inhibition in human primary breast organoids

This study shows cadmium exposure inhibits branching morphogenesis and HIF-1α activity in human breast organoids, suggesting it disrupts mammary gland development rather than promoting cancer.