BioengineeringbioRxiv
Nanoconfinement of Microvilli Alters Gene Expression and Boosts T cell Activation
M. Aramesh, D. Stoycheva, I. Sandu…·E. Klotzsch
This study shows that nanoporous surfaces enhance T cell activation by altering gene expression and promoting microvilli formation through size-dependent protein segregation.
DOI 10.1073/pnas.2107535118