Cell BiologybioRxiv
Modeling of Aberrant Epithelial Reprogramming in Idiopathic Pulmonary Fibrosis using Human Induced Pluripotent Stem Cell-derived Alveolar Organoids
V. Ptasinski, S. J. Monkley, K. Ost…·L. A. Murray
This study develops a human iPSC-derived alveolar organoid model of IPF that recapitulates epithelial reprogramming and responds to antifibrotic drugs.