PathologybioRxivPreprint
PKA drives paracrine crisis and WNT4-dependent testis tumor in Carney complex
C. Djari, I. Sahut-Barnola, A. Septier…·A. M. Lefrancois-Martinez
The paper investigates the role of PKA in Carney complex testis tumors, showing that Prkar1a mutations in both stromal and Sertoli cells drive LCCSCTs via WNT4-dependent paracrine signaling.
DOI 10.1101/2020.12.21.423735