BiochemistrybioRxiv
Optimizing Phosphopeptide Structures That Target 14-3-3ϵ in Cutaneous Squamous Cell Carcinoma
S. Kamayirese, S. Maity, L. M. Dieckman…·S. Lovas
This paper optimizes a phosphopeptide inhibitor of the 14-3-3ϵ-CDC25A interaction in cutaneous squamous cell carcinoma, achieving nanomolar affinity through peptide shortening and amino acid modification.
DOI 10.1021/acsomega.3c07740