ImmunologybioRxiv
Preclinical validation of a second generation leishmanization vaccine against vector transmitted fatal visceral leishmaniasis
H. L. Nakhasi, R. DEY, S. Gannavaram…·K. Pandey
This study evaluates the protective efficacy of a CRISPR-edited Leishmania major strain against visceral leishmaniasis in hamsters and shows it induces a pro-inflammatory immune response and prevents disease.
DOI 10.1038/s42003-021-02446-x