Using cGMP analogues to modulate photoreceptor light sensitivity: Perspectives for the treatment of retinal degeneration.
S. Wucherpfennig, W. Haq, V. Popp, S. Kesh, S. Das, C. Melle, A. Rentsch, F. Schwede, F. Paquet-Durand, V. Nache
The paper presents a strategy using cGMP analogues to selectively modulate rod or cone photoreceptor function in retinal degeneration, preserving normal CNG-channel function.
bioRxiv · Feb 7, 2022 · PreprintPhysiology