Cyclophilin A protects HIV-1 from restriction by human TRIM5α
K. Kim, A. Dauphin, S. Komurlu, L. Yurkovetskiy, W. E. Diehl, S. M. McCauley, C. Carbone, C. Strambio-De-Castillia, E. M. Campbell, J. Luban
This study shows that Cyclophilin A protects HIV-1 from restriction by human TRIM5α by shielding the viral capsid from early inhibition during infection.
bioRxiv · Aug 24, 2019Microbiology