Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
N. Youssef, S. Gurev, F. Ghantous, K. P. Brock, J. A. Jaimes, N. N. Thadani, A. Dauphin, A. C. Sherman, L. Yurkovetskiy, D. Soto, R. Estanboulieh, B. Kotzen, P. Notin, A. W. Kollasch, A. A. Cohen, , D. Marks
The paper designs SARS-CoV-2 Spike proteins with novel mutations to evaluate vaccine effectiveness against future viral variants using a deep learning model.
bioRxiv · Oct 8, 2023Immunology
L. Yurkovetskiy, S. Egri, C. Kurhade, M. A. Diaz-Salinas, J. A. Jaimes, T. Nyalile, X. Xie, M. C. Choudhary, A. Dauphin, J. Z. Li, J. B. Munro, P.-Y. Shi, K. Shen, J. Luban
This study shows that S:D614G and S:H655Y mutations enhance SARS-CoV-2 infectivity by stabilizing the Spike protein in an open RBD conformation, acting epistatically with the polybasic S1/S2 cleavage site.
bioRxiv · Mar 30, 2023 · PreprintMicrobiology
F. Crozet, G. Letort, C. Da Silva, A. Eichmuller, A. F. Tortorelli, M. Belle, J. Dumont, T. Piolot, A. Dauphin, F. Coulpier, A. Chedotal, J.-L. Maitre, M.-H. Verlhac, H. Clarke, M.-E. Terret
This study shows that TZPs, formed by Myosin-X, support oocyte-matrix integrity and gene expression, affecting mouse fertility.
bioRxiv · Sep 15, 2022 · PreprintCell Biology
O. Faklaris, L. Bancel-Vallee, A. Dauphin, B. Monterroso, P. Frere, D. Geny, T. Manoliu, S. de Rossi, F. P. Cordelieres, D. Schapman, R. Nitschke, J. Cau, T. Guilbert
This paper develops automated protocols and metrics for long-term light microscope quality assessment and monitoring using accessible tools and an ImageJ plugin.
bioRxiv · Jun 16, 2021Scientific Communication & Education
L. Yurkovetskiy, X. Wang, K. E. Pascal, C. Tompkins-Tinch, T. Nyalile, Y. Wang, A. Baum, W. E. Diehl, A. Dauphin, C. Carbone, K. Veinotte, S. B. Egri, S. F. Schaffner, J. E. Lemieux, J. Munro, , J. Luban
This study shows the D614G SARS-CoV-2 spike protein variant is more infectious but has reduced ACE2 affinity and altered trimer conformation, affecting viral entry and antibody neutralization.
bioRxiv · Jul 4, 2020Microbiology
K. Kim, A. Dauphin, S. Komurlu, L. Yurkovetskiy, W. E. Diehl, S. M. McCauley, C. Carbone, C. Strambio-De-Castillia, E. M. Campbell, J. Luban
This study shows that Cyclophilin A protects HIV-1 from restriction by human TRIM5α by shielding the viral capsid from early inhibition during infection.
bioRxiv · Aug 24, 2019Microbiology
J. I. Boucher, T. W. Whitfield, A. Dauphin, G. Nauchum, K. B. Zeldovich, R. Swanstrom, C. A. Schiffer, J. Luban, D. N. A. Bolon
The paper investigates HIV-1 protease evolution by comparing experimental fitness landscapes with sequenced isolate data, showing mutational sampling influences multiple mutations.
bioRxiv · Jan 28, 2019Evolutionary Biology
S. M. McCauley, K. Kim, A. Nowosielska, A. Dauphin, W. E. Diehl, J. Luban
The paper shows that HIV-1 provirus RNA activates innate immune responses through post-transcriptional elements, suggesting new therapeutic targets.
bioRxiv · Apr 5, 2018Microbiology