Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike
M. A. Diaz-Salinas, Q. Li, M. Ejemel…·J. B. Munro
This study investigates how ACE2 and antibodies affect the conformational dynamics of the SARS-CoV-2 spike protein using smFRET and FCS, revealing that D614G modulates RBD energetics similar to ACE2 binding.