Author

S. L. Miles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Organism:E. coli· 1

Frequent Co-Authors

S. Mostowy· 3 shared V. Torraca· 3 shared C. Jenkins· 2 shared A. T. Lopez-Jimenez· 1 shared B. Wang· 1 shared C. E. Chong· 1 shared D. A. Oyarzun· 1 shared D. Brokatzky· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

S. Mostowy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Shigella serotypes associated with carriage in humans establish persistent infection in zebrafish

V. Torraca, D. Brokatzky, S. L. Miles, C. E. Chong, P. M. De Silva, S. Baker, C. Jenkins, K. E. Holt, K. S. Baker, S. Mostowy

This paper shows that three Shigella serotypes associated with MSM transmission can establish persistent infection in zebrafish, failing to promote macrophage cell death.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology

Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive Escherichia coli

S. L. Miles, V. Torraca, Z. A. Dyson, A. T. Lopez-Jimenez, E. Foster-Nyarko, C. Jenkins, K. Holt, S. Mostowy

The paper shows that acquisition of the pINV plasmid in ST99 E. coli made its virulence temperature-dependent, aiding global dispersal.

bioRxiv · Oct 27, 2022 · PreprintMicrobiology

P1 bacteriophage-enabled delivery of CRISPR-Cas9 antimicrobial activity against Shigella flexneri

Y. W. Huan, V. Torraca, R. Brown, J. Fa-arun, S. L. Miles, D. A. Oyarzun, S. Mostowy, B. Wang

This study uses a P1 bacteriophage to deliver CRISPR-Cas9 for targeted killing of Shigella flexneri in zebrafish larvae, reducing bacterial load and improving survival.

bioRxiv · Sep 2, 2022Microbiology