Cell BiologybioRxiv
BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 implicated in Tau pathology
M. Taga, V. A. Petyuk, C. White…·P. L. De Jager
The paper identifies BIN1 protein isoforms expressed in astrocytes, neurons, and microglia, finding that neuronal and astrocytic BIN1 containing exon 7 is associated with tau pathology in Alzheimer's disease.
DOI 10.1186/s13024-020-00387-3