ImmunologybioRxivPreprint
Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression
J. S. Dolina, J. Lee, S. E. Brightman…·S. P. Schoenberger
This study shows that combining CD4+/CD8+ T cell neoantigen vaccination with immune checkpoint blockade overcomes resistance and enables tumor regression in low TMB cancers.
DOI 10.1101/2023.05.06.539290