Author

S. M. Lyons

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Aulas· 2 shared M. Lesniczak· 2 shared P. Anderson· 2 shared P. Ivanov· 2 shared W. Szaflarski· 2 shared A. Emili· 1 shared A. Rodriguez-Vargas· 1 shared A. S. Gladfelter· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

A. Aulas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of Mul1-mediated ubiquitination promotes mitochondria-associated translation

Y. Gao, M. D. Cardamone, J. Kwan, R. Hekman, J. Orofino, S. M. Lyons, A. Emili, V. Perissi

The paper identifies GPS2 as an inhibitor of Mul1-mediated ubiquitination that regulates mitochondria-associated translation by targeting RNA-binding and translation factors.

bioRxiv · Jul 28, 2021 · PreprintCell Biology

Mechanisms of translation inhibition and suppression of Stress Granule formation by cisplatin

P. Pietras, A. Aulas, M. M. Fay, M. Lesniczak, S. M. Lyons, W. Szaflarski, P. Ivanov

This study identifies cisplatin's mechanism of cytotoxicity through translation inhibition and suppression of stress granule formation, explaining its toxic effects.

bioRxiv · Jul 20, 2021Cell Biology

A Novel Stress Response Pathway Regulates Ribosome Biogenesis

W. Szaflarski, M. Sowinski, M. Lesniczak, S. Ojha, A. Aulas, D. Dave, S. Malla, P. Anderson, P. Ivanov, S. M. Lyons

This study identifies a novel stress response pathway, RiBiSR, that regulates rRNA processing and ribosome biogenesis independently of the ISR to conserve energy and maintain the nucleolus.

bioRxiv · Aug 16, 2020 · PreprintBiochemistry

Regulation of FXR1 by alternative splicing is required for muscle development and controls liquid-like condensates in muscle cells

J. A. Smith, E. G. Curry, R. E. Blue, C. Roden, S. E. R. Dundon, A. Rodriguez-Vargas, D. C. Jordan, X. Chen, S. M. Lyons, J. Crutchley, P. Anderson, M. E. Horb, A. S. Gladfelter, J. Giudice

This study shows that alternative splicing of FXR1 regulates its function in muscle development by controlling RNA-dependent condensates and disease-related mis-splicing.

bioRxiv · Oct 24, 2019Cell Biology