Author

J. Kwan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Emili· 4 shared J. Orofino· 2 shared M. D. Cardamone· 2 shared V. Perissi· 2 shared Y. Gao· 2 shared A. J. Hume· 1 shared A. Karki· 1 shared C. Gao· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCell Biology

A. Emili

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling

S. S. Kim, I. Kycia, M. Karski, R. K. Ma, E. A. Bordt, J. Kwan, A. Karki, E. Winter, R. G. Aktas, Y. Wu, A. Emili, D. E. Bauer, P. Sethupathy, K. Vakili

The paper engineers a DNAJB1-PRKACA fusion in HEK293T cells to study its oncogenic effects, finding LINC00473 overexpression dependent on PKA signaling.

bioRxiv · Aug 11, 2021Cancer Biology

Inhibition of Mul1-mediated ubiquitination promotes mitochondria-associated translation

Y. Gao, M. D. Cardamone, J. Kwan, R. Hekman, J. Orofino, S. M. Lyons, A. Emili, V. Perissi

The paper identifies GPS2 as an inhibitor of Mul1-mediated ubiquitination that regulates mitochondria-associated translation by targeting RNA-binding and translation factors.

bioRxiv · Jul 28, 2021 · PreprintCell Biology

ADP-ribosylation of mitochondrial proteins is mediated by Neuralized-like protein 4 (NEURL4)

M. D. Cardamone, Y. Gao, J. Kwan, V. Hayashi, M. Sheeran, J. Xu, J. English, J. Orofino, A. Emili, V. Perissi

This study identifies NEURL4 as the main mitochondrial ADP-ribosyltransferase and shows it regulates mtDNA integrity through poly-ADP-ribosylation of mtLIG3.

bioRxiv · Dec 28, 2020Cell Biology

SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors

C. Gao, J. Zeng, N. Jia, K. Stavenhagen, Y. Matsumoto, H. Zhang, J. Li, A. J. Hume, E. Muehlberger, I. van Die, J. Kwan, K. Tantisira, A. Emili, R. D. Cummings

This study identifies multiple innate immune receptors that recognize SARS-CoV-2 spike protein through glycan-dependent interactions, suggesting potential therapeutic targets.

bioRxiv · Jul 29, 2020 · PreprintBiochemistry