BioengineeringbioRxiv
Rapid Adeno-Associated Virus Genome Quantification with Amplification-Free CRISPR-Cas12a
Z. Hetzler, S. M. Marinakos, N. Lott…·Q. Wei
The paper develops a CRISPR-based assay to rapidly and accurately quantify AAV genome titers, enabling efficient manufacturing of rAAV vectors.
DOI 10.1038/s41434-024-00449-x