S. M. Ponik

This paper introduces a one-pot exosome proteomics method using a photocleavable surfactant, enabling rapid and effective exosomal lysis, protein extraction, and digestion, with high reproducibility and coverage.

This study converts pro-tumor CAFs to anti-tumor CAFs using Meflin induction, enhancing PDAC chemosensitivity through improved drug delivery and reduced tissue stiffness.

This study shows that collagen fiber alignment affects cell-scale stiffness and mechanosensory signal propagation, influencing cell behavior and communication in the tumor microenvironment.

The paper introduces an improved exosome reporter, pHluorin-CD63 with M153R mutation, enabling stable visualization of exosome secretion and uptake in live cells and reveals their role in cell migration.