Author

S. M. Rocha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. Lewis· 3 shared R. B. Tjalkens· 3 shared T. Schountz· 3 shared A. Fagre· 2 shared M. Eckley· 2 shared S. Zhan· 2 shared A. C. Fagre· 1 shared A. Corper· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

J. Lewis

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3 papers

Recent·Most cited

A novel glucocorticoid and androgen receptor modulator reduces viral entry and innate immune inflammatory responses in the Syrian Hamster model of SARS-CoV-2

S. M. Rocha, A. C. Fagre, A. S. Latham, K. A. Popichak, C. P. McDermott, C. C. Dawson, J. Lewis, P. Reigan, T. A. Aboellail, R. C. Kading, T. Schountz, N. D. Theise, R. A. Slayden, R. B. Tjalkens

This paper shows that PT150, a glucocorticoid and androgen receptor antagonist, reduces SARS-CoV-2 replication and inflammatory responses in Syrian hamsters.

bioRxiv · Feb 20, 2021Immunology

A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters

A. Fagre, J. Manhard, R. Adams, M. Eckley, S. Zhan, J. Lewis, S. M. Rocha, C. Woods, K. Kuo, W. Liao, L. Li, A. Corper, D. Challa, E. Mount, C. Tumanut, , T. Schountz

bioRxiv · Sep 25, 2020Microbiology

SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

A. Fagre, J. Lewis, M. Eckley, S. Zhan, S. M. Rocha, N. R. Sexton, B. Burke, B. J. Geiss, O. Peersen, R. Kading, J. Rovnak, G. D. Ebel, R. B. Tjalkens, T. Aboellail, T. Schountz

This study infects deer mice with SARS-CoV-2, showing robust replication and potential for natural transmission, with a new spike protein mutation emerging during in vivo passage.

bioRxiv · Aug 7, 2020Microbiology