S. Zhan

Coordinated molecular and ecological adaptations underlie a highly successful parasitoid

This study identifies molecular and ecological adaptations in the parasitoid Trichopria drosophilae that enhance its success in parasitizing Drosophila hosts.

Regulatory T Cell-like Response to SARS-CoV-2 in Jamaican Fruit Bats Transduced with Human ACE2

This study shows Jamaican fruit bats are poorly susceptible to SARS-CoV-2 but develop a regulatory T cell-like immune response when transduced with human ACE2, leading to lung infection without overt disease.

SARS-CoV-2 infects multiple species of North American deer mice and causes clinical disease in the California mouse

This study shows SARS-CoV-2 infects multiple North American deer mice and causes clinical disease in California mice, suggesting potential wildlife reservoirs and co-morbidity factors for severe COVID-19.

Assessing the zoonotic potential of a novel bat morbillivirus

This study identifies a novel bat morbillivirus, MBaMV, and assesses its zoonotic potential by showing it can infect human cells but is restricted by human immune responses.

Animal chromosome counts reveal similar range of chromosome numbers but with less polyploidy in animals compared to flowering plants

The paper introduces the Animal Chromosome Count database and finds similar chromosome number distributions between animals and flowering plants, with less polyploidy in animals.

Reactivities of the Front Pocket N-Cap Cysteines in Human Kinases

This study uses CpHMD simulations to analyze cysteine reactivity in kinase N-cap positions, finding that some are reactive while others are not, depending on nearby residues.

A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters

SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

This study infects deer mice with SARS-CoV-2, showing robust replication and potential for natural transmission, with a new spike protein mutation emerging during in vivo passage.

Dual oxidase gene Duox and Toll-like receptor 3 gene TLR3 in the Toll pathway suppress zoonotic pathogens through regulating the intestinal bacterial community homeostasis in Hermetia illucens L.

This study investigates how Duox and TLR3 genes in Hermetia illucens larvae suppress zoonotic pathogens by modulating intestinal bacterial community homeostasis through immune signaling pathways.

Whole genome sequencing of 358 brown planthoppers uncovers the landscape of their migration and dispersal worldwide

This study sequenced 358 brown planthopper genomes to reveal genetic structure and dispersal patterns, identifying five genetic groups and highlighting Southeast Asia as a major source for East Asian populations.