W. Liao

SlNAP2 promoted fruit ripening by directly binding the ACS2 promoter and interacting with EIL3

This study identifies SlNAP2 as a NAC transcription factor that promotes tomato fruit ripening by directly binding the ACS2 promoter and interacting with EIL3 to enhance ethylene signaling.

Os-circANK negatively regulates resistance to bacterial blight in rice via Osa-miR398b/OsCSD1/OsCSD2 pathways

The paper identifies Os-circANK as a circRNA that suppresses rice resistance to bacterial blight by sponging Osa-miR398b and modulating OsCSD1/OsCSD2 expression.

Degradation of indole-3-acetic acid by plant-associated microbes

This study identifies bacterial isolates capable of degrading indole-3-acetic acid (IAA) from Arabidopsis and rice roots, revealing their functional roles and association with IAA producers.

IOBR2: Multidimensional Decoding Tumor Microenvironment for Immuno-Oncology Research

IOBR2 is a tool for analyzing tumor microenvironment using multi-omics data, offering modules for preprocessing, estimation, interaction analysis, and visualization.

Platelet-specific TGFβ1 deficiency aggravates atherosclerosis, vascular inflammation, and hypercholesterolemia in mice

Mass cytometry identifies dysregulation of circulating and cutaneous immune cells in patients with hidradenitis suppurativa

This study identifies immune cell dysregulation in hidradenitis suppurativa using mass cytometry and RNA-seq, finding increased CD38 expression in monocytes and suggesting CD38 as a therapeutic target.

Investigation of a mathematical model describing global cancer growth and treatment: An inhomogeneous model based on the generalized logistic equation

This paper introduces an inhomogeneous mathematical model based on the generalized logistic equation to describe tumor growth and treatment, validated against clinical observations and theories of tumor heterogeneity.

Barley powdery mildew effector CSEP0162 targets multivesicular body-associated MON1 important for immunity

The paper identifies CSEP0162 as a barley powdery mildew effector that targets MON1, inhibiting encasement formation and HR, highlighting MON1's role in plant immunity.

TGF--dependent Lymphoid Tissue Residency of Stem-like T cells Limits the Response to Tumor Vaccine

The paper identifies TGF-β-dependent differentiation of stem-like CD8+ T cells into tissue-resident memory T cells in tumor draining lymph nodes, which negatively correlates with tumor vaccine response.

Ciliated protozoa from industrial WWTP activated sludge: a biodiversity survey including trophic interactions and redescription of Bakuella subtropica (Spirotrichea, Hypotrichia) according to Next Generation Taxonomy

The paper characterizes ciliate communities in a wastewater treatment plant, identifies trophic interactions, and redescribes a species using modern taxonomy.

A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters

Comparison of motility of H. pylori in broth and mucin reveals the interplay of effect of acid on bacterium and the rheology of the medium it swims in.

This study compares H. pylori motility in broth and mucin under varying pH conditions, revealing how acid affects bacterial movement and interacts with the rheology of the medium.

One New Species of the Genus Dryomys (Rodentia, Glirgae) from Xinjiang China, Dryomys Yarkandensis sp. nov

The paper describes a new species of rodent, Dryomys yarkandensis, discovered in Xinjiang, China, and compares it to other Dryomys species based on morphological characteristics.

Targeting the mTORC2 signaling complex in B cell malignancies.

This study identifies novel inhibitors that disrupt the mTORC2 complex and induce apoptosis in chronic lymphocytic leukemia cells more effectively than existing treatments.

Hypothalamic transcriptome analysis reveals the neuroendocrine mechanisms in controlling broodiness of Muscovy duck (Cairina moschata)

The paper analyzes the hypothalamic transcriptome of Muscovy ducks across reproductive stages to identify gene expression changes and pathways involved in broodiness.