ImmunologybioRxivPreprint
Enhanced neutralization potency of an identical HIV neutralizing antibody expressed as different isotypes is achieved through genetically distinct mechanisms
T. Moyo-Gwete, C. Scheepers, Z. Makhado…·P. L. Moore
This study investigates how different isotypes of the same HIV-neutralizing antibody achieve enhanced neutralization potency through distinct mechanisms involving hinge and CH1 regions.
DOI 10.1101/2022.08.17.504233