BiochemistrybioRxiv
Fast and efficient digestion of adeno associated virus (AAV) capsid proteins for liquid chromatography mass spectrometry (LC-MS) based peptide mapping and post translational modification analysis (PTMs)
F. Guapo, L. Strasser, S. Millan-Martin…·J. Bones
The paper describes a fast method to digest AAV5 capsid proteins for LC-MS peptide mapping and PTM analysis, achieving 100% sequence coverage.
DOI 10.1016/j.jpba.2021.114427