Author

S. Moorthi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Berger· 2 shared A. K. Riley· 1 shared A. Lo· 1 shared A. Snell· 1 shared A. Urisman· 1 shared A. Vichas· 1 shared F. Mundt· 1 shared I. Fung· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. Berger

Mutual co-authors in cluster

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3 papers

Recent·Most cited

The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes

A. K. Riley, M. Grant, A. Snell, A. Vichas, S. Moorthi, A. Urisman, P. Castel, L. Wan, A. Berger

This study shows that USP9X stabilizes RIT1 protein and that its depletion reduces RIT1 abundance and sensitizes cells to EGFR inhibitors.

bioRxiv · Nov 30, 2023Cancer Biology

Fending for oneself or partnering up: Competition between mixo- and heterotrophic ciliates under dynamic resource supply

S. Flöder, T. Klauschies, M. Klaassen, T. Stoffers, M. Lambrecht, S. Moorthi

This study examines how mixotrophic and heterotrophic ciliates compete under varying resource supply conditions, showing that population dynamics depend on species-specific traits and resource regimes.

bioRxiv · Nov 6, 2023 · PreprintEcology

Mapping the unique and shared functions of oncogenic KRAS and RIT1 with proteome and transcriptome profiling

A. Lo, K. Holmes, F. Mundt, S. Moorthi, I. Fung, S. Fereshetian, J. Watson, S. A. Carr, P. Mertins, A. Berger

This study compares proteomic and transcriptomic profiles of KRAS and RIT1 mutant lung cells to identify shared and divergent functions in oncogenic signaling.

bioRxiv · Apr 10, 2020 · PreprintCancer Biology