Author
A. Lo
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2022 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author links7 papers
Recent·Most cited
Distinct cell adhesion signature defines glioblastoma myeloid-derived suppressor cell subsets
D. Bayik, C. F. Bartels, K. Lovrenert, D. Watson, D. Zhang, K. Kay, A. Lauko, S. Johnson, A. Lo, M. McGraw, M. Grabowski, A. M. Mohammadi, F. Veglia, Y. Fan, M. A. Vogelbaum, , J. Lathia
The paper identifies distinct cell adhesion signatures in glioblastoma myeloid-derived suppressor cell subsets, showing that monocytic MDSCs drive tumor growth through enhanced integrin β1 expression.
bioRxiv · Sep 27, 2021Immunology
Fine tuning the mechanism of Antigen 43 self-association to modulate aggregation levels of Escherichia coli pathogens
J. Vo, G. C. Martinez Ortiz, M. Totsika, A. Lo, A. E. Whitten, L. Hor, K. M. Peters, V. Ageorges, N. Caccia, M. Desvaux, M. A. Schembri, J. J. Paxman, B. Heras
The paper investigates the role of Ag43 homologues in bacterial aggregation and biofilm formation, revealing a common trans-association mechanism and how variations in these interactions affect aggregation kinetics.
bioRxiv · Apr 19, 2021 · PreprintBiochemistry
Mapping the unique and shared functions of oncogenic KRAS and RIT1 with proteome and transcriptome profiling
A. Lo, K. Holmes, F. Mundt, S. Moorthi, I. Fung, S. Fereshetian, J. Watson, S. A. Carr, P. Mertins, A. Berger
This study compares proteomic and transcriptomic profiles of KRAS and RIT1 mutant lung cells to identify shared and divergent functions in oncogenic signaling.
bioRxiv · Apr 10, 2020 · PreprintCancer Biology
Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner
D. Bayik, Y. Zhou, C. Park, C. Hong, D. Vail, D. J. Silver, A. J. Lauko, G. A. Roversi, D. C. Watson, A. Lo, T. J. Alban, M. McGraw, M. D. Sorensen, M. M. Grabowski, B. Otvos, , J. Lathia
This study identifies sex-specific roles of MDSC subsets in glioblastoma, showing mMDSCs drive growth in males and gMDSCs in females, with potential therapeutic targets.
bioRxiv · Feb 19, 2020Immunology
Cholangiocarcinoma presents a distinct myeloid-derived suppressor cell signature compared to other hepatobiliary cancers
D. Bayik, A. Lauko, G. A. Roversi, E. Serbinowski, L.-A. Acevedo-Moreno, C. Lanigan, M. Orujov, A. Lo, T. Alban, D. J. Silver, J. M. Brown, D. S. Allende, F. N. Aucejo, J. D. Lathia
The paper identifies a distinct myeloid-derived suppressor cell (MDSC) signature in cholangiocarcinoma (CCA) compared to other hepatobiliary cancers, linking MDSC levels to disease outcomes and potential therapeutic targets.
bioRxiv · Dec 11, 2019 · PreprintPathology
Temporal-Spatial Visualization of Endogenous Chromosome Rearrangements in Living Cells
H. Wang, M. Nakamura, D. Zhao, C. M. Nguyen, C. Yu, A. Lo, T. Daley, M. La Russa, Y. Liu, L. S. Qi
This paper introduces LiveFISH, a method to visualize real-time chromosomal rearrangements in living cells, and demonstrates its application in detecting gene-editing induced translocations.
bioRxiv · Aug 14, 2019 · PreprintBioengineering