S. O'Reilly

SARS-CoV-2 infects neurons, astrocytes, choroid plexus epithelial cells and pericytes of the human central nervous system

This study shows SARS-CoV-2 can infect neurons, astrocytes, choroid plexus epithelial cells, and pericytes in the human central nervous system, supporting a model of direct viral infection as a cause of neurological symptoms in COVID-19.

A novel antiviral formulation inhibits SARS-CoV-2 infection of human bronchial epithelium

This study demonstrates that ViruSAL inhibits SARS-CoV-2 infection in human bronchial epithelial cells and rat models without causing toxicity.

Bile acid-CoA:amino acid N-acyltransferase gene knockout alters early life development, the gut microbiome and reveals unusual bile acid conjugates in mice

This study shows that BAAT gene deletion in mice leads to altered bile acid conjugation, microbiome changes, and unusual bile acid conjugates, with potential rescue by other enzymes.

Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH

This paper shows that PTPRH mutations in NSCLC lead to elevated EGFR phosphorylation, which can be targeted by existing EGFR inhibitors.