Cell BiologybioRxiv
A Sterol-PI(4)P exchanger controls the Tel1/ATM axis of the DNA Damage Response
S. Ovejero, S. Kumanski, C. Soulet…·M. Moriel-Carretero
The paper shows that lipid droplets modulate the DNA Damage Response by stabilizing PI(4)P at the Golgi, which affects ATM activity and DNA repair kinetics.
DOI 10.15252/embj.2022112684